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Protein Biochemistry
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Vincristine (sulfate)
Vincristine (sulfate) from Cayman Chemical
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Citations:
(9)
Supplier Page
Supplier Page from
Cayman Chemical for
Vincristine (sulfate)
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Description
An antimitotic vinca alkaloid which irreversibly blocks mitosis by binding to tubulin (Ki = 85 nM) and inhibiting tubulin polymerization; exported from cells via the ABC transporter P-glycoprotein but not by Mrp1
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Vincristine (sulfate)
Company
Cayman Chemical
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
11764
Quantity
25 mg
Research Area
Cancer, Cell Biology, Cytoskeleton & Motor Proteins
Format
A crystalline solid
Molecular Weight
923
Purity
≥95%
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (9)
(1)
Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia
Cancers (Basel)
December 15, 2023
Johnson Ung, Su-Fern Tan, Todd E. Fox, Jeremy J. P. Shaw, Maansi Taori, Bethany J. Horton, Upendarrao Golla, Arati Sharma, Zdzislaw M. Szulc, Hong-Gang Wang,
et al.
during routine
cell culture
. HL-60/VCR [23] were supplemented with 1 μg/mL vincristine sulfate (
Cayman
, #
11764
). ABT737 (
Cayman
, #
11501
) was supplemented to ABT737R cell lines: HL-60/ABT737R [24] (5 μM ABT737);
(2)
TK216 targets microtubules in Ewing sarcoma cells
Cell Chemical Biology
August 18, 2022
Juan Manuel Povedano, Vicky Li, Katherine E. Lake, Xin Bai, Rameshu Rallabandi, Jiwoong Kim, Yang Xie, Jef K. De Brabander, David G. McFadden
Colchicine
was purchased from
Sigma-Aldrich
(#
C9754
-100MG). Vincristine was purchased from
Cayman Chemical
(#
11764
).
YK-4-279
was purchased from
Selleck Chemicals
(#
S7679
). TK216 was purchased from MedChem Express (#HY-122903).
(3)
The RNA-Binding Protein Musashi1 Regulates a Network of Cell Cycle Genes in Group 4 Medulloblastoma
Cells
December 25, 2021
Baroni M, Guardia GDA, Lei X, Kosti A, Qiao M, Landry T, Mau K, Galante PAF, Penalva LOF.
L9283
; Cat#
D8418
). Vincristine was obtained from
Cayman Chemical Company
, Ann Harbor, MI, USA (Cat#
11764
). 2.3.
Cell Transfection
and siRNA
Knockdown
CHLA-01 and CHLA-01R cells were transiently
transfected
(4)
Ceramide Analogue SACLAC Modulates Sphingolipid Levels and
MCL-1
Splicing to Induce Apoptosis in Acute Myeloid Leukemia
Molecular cancer research : MCR
March 1, 2020
Pearson JM, Tan SF, Sharma A, Annageldiyev C, Fox TE, Abad JL, Fabrias G, Desai D, Amin S, Wang HG,
et al
.
10% FBS. HL-60/VCR (33) cells were maintained in the presence
of 1
μg/ml vincristine sulfate (
Cayman
#
11764
). HL-60/ABTR (34) cells were maintained in the presence of 5 μM
ABT-737
(
Cayman
#
11501
). KG1/ABTR and
(5)
DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome
Nature
September 1, 2019
Samir P, Kesavardhana S, Patmore DM, Gingras S, Malireddi RKS, Karki R, Guy CS, Briard B, Place DE, Bhattacharya A,
et al
.
Aesar,
36404
), 2 μg ml−1 thapsigargin (
Cayman Chemical
,
10522
), 750 μM vincristine39 (
Cayman Chemical
,
11764
), 400 μM paclitaxel (
Cayman Chemical
,
10461
) and 5 μM RK-33 (Selleckchem, S8246) were added for 30 min
(6)
Mammalian cell growth dynamics in mitosis
eLife
May 7, 2019
Miettinen TP, Kang JH, Yang LF, Manalis SR.
drug",Vinblastine,
Cayman Chemical
,Cat#
11762
; CAS:143-67-9, "Chemical compound, drug",Vincristine,
Cayman Chemical
,Cat#
11764
; CAS:2068-78-2, "Chemical compound, drug",
TORIN-1
,
Tocris Bioscience
,Cat#4247; CAS: 1222998-36-8, "Chemical
(7)
Follicular lymphoma–associated mutations in vacuolar ATPase ATP6V1B2 activate autophagic flux and mTOR
Journal of Clinical Investigation
March 4, 2019
Fangyang Wang et al.
torin 1
(catalog
10997
), doxorubicin (catalog
15007
), dexamethasone (catalog
11015
), vincristine (catalog
11764
), and chloroquine (catalog
14194
), all procured from
Cayman Chemical
, were diluted serially in medium,
(8)
IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers
The Journal of clinical investigation
April 2, 2018
Xie H, Tang CH, Song JH, Mancuso A, Del Valle JR, Cao J, Xiang Y, Dang CV, Lan R, Sanchez DJ,
et al
.
4μ8c (catalog 412512) was from Millipore. SCDi (catalog Cay10012562) and vincristine sulfate (catalog
11764
) were purchased from
Cayman
. U-13C-glucose (catalog CLM1396) was from Cambridge Isotope Laboratories. Plasmids,
(9)
Tissue and spine regeneration in the temperate sea urchin
Psammechinus miliaris
Invertebrate Reproduction & Development
April 3, 2017
Leah R. Brown, Gary S. Caldwell
were then removed. 90 22-oxo-vincaleukoblastine sulphate (vincristine sulphate,
Cayman Chemical
,
11764
) was 91 diluted into calcium- and magnesium-free artificial seawater (460 mM NaCl, 10 mM KCl, 7 92 mM
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Vincristine (sulfate) from Cayman Chemical
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